 |
|
|
|
|
 |
 |
Tobacco-related Malignancy Center of Economic Excellence
Inception: About the CoEE: The CoEE in Tobacco-Related Malignancy is devoted to discovering biomarkers of tobacco-related malignancies. The initial focus is on lung cancer, but CoEE leaders also hope to make advances in other tobacco-related malignancies including head and neck, bladder, and esophageal cancers. The CoEE’s goals include (a) identifying biomarkers of tobacco-related malignancies using genomics, proteomics, and lipidomics; (b) employing techniques to validate biomarkers; (c) integrating bioinformatics to evaluate discovery efforts and to mine cancer databases; (d) developing a networked tissue repository; and (e) developing and implementing clinical trials to evaluate new biomarker uses. The CoEE, in conjunction with the Hollings Cancer Center (HCC), will partner with the U.S. Department of Veteran Affairs, DHEC, the S.C. Cancer Alliance, and other state hospital systems. These same partners, along with HSSC and the Medical University Hospital Authority, will work with the CoEE to develop a distributed tissue repository and a clinical trials network. In 2008, the CoEE, in conjunction with HCC, has formed an alliance with the University of Colorado Comprehensive Cancer Center on a renewal of an NCI-funded Specialized Center of Research Excellence (SPORE) in Lung Cancer. Two faculty members associated with the CoEE, Drs. Gemmill and Drabkin, have clinical trials partnerships with Syndax, Pfizer, and Novartis for more than $1.25 million in funding. Other faculty
members associated with the CoEE enrolled a record number of patients with head, neck and thoracic cancers into therapeutic clinical trials this
past year, representing 14% of patients in these disease areas seen at HCC. Since inception, the CoEE has received more than $3.8 million in federal and private research funding. The CoEE also participated in the application of the NCI Cancer Center Designation award and the $20 million NIH Clinical and Translational Science Award. Funding level: CoEE endowed chair:
|
