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Molecular Proteomics and Cardiovascular Disease and Prevention Center of Economic Excellence
Inception: About the Center: This Center advances cardiovascular (CV) prevention and treatment “bench” science into clinical “bedside” care. This Center’s primary goals include (a) developing measurement systems to detect early heart failure indicators; (b) relating diagnostic protein signatures to clinical outcomes; (c) developing therapeutic management strategies; (d) creating a statewide network to develop, test, and improve clinical care of heart failure; and (e) transferring technology into new South Carolina industries. In 2008, the Center began a statewide network of five primary, separate care locations to participate and be linked by a central bioinformatics core. This core will allow patients who currently suffer or are at risk for CV disease from across the state to be screened. In 2009, plasma screening was conducted for 450 patients. Through this screening, 16 plasma proteins were analyzed and a specific biomarker portfolio was created for the diagnosis and prediction of left ventricular hypertrophy and diastolic heart failure. Funding level: SmartState Endowed Chairs:
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